“Let the Right One In” helmer Tomas Alfredson will direct Nicole Kidman in true-life sex-change drama “The Danish Girl.”

Lucinda Coxon penned the script based on David Ebershoff’s novel about Danish painter Einar Wegener (Kidman), who in 1931 became the first person to go through a sex-change operation to become a woman.

However, Charlize Theron, who had been attached to play Wegener’s wife, Gerda, has left the production.

Pic will be produced by Kidman and Per Saari, head of Kidman’s Fox-based Blossom Films shingle, along with Anne Harrison, Gail Mutrux and Linda Reisman.

“We have been in talks for close to a year, and we are soon going into production,” Alfredson told Daily Variety.

Alfredson said he planned to shoot “The Danish Girl” before his previously announced John le Carre adaptation, “Tinker, Tailor, Soldier, Spy,” for Working Title.